Retinitis Pigmentosa (Night Blindness)
Retinitis pigmentosa is an inherited disease of the retina that begins with poor night vision and loss of side vision and progresses slowly. An approved gene therapy exists for the RPE65-related type; for other types, low-vision support and follow-up are important.
What is retinitis pigmentosa?
In Turkish it is popularly called 'tavuk karası'. The retinal cells that allow us to see in the dark gradually stop working. It is an inherited disease with several inheritance patterns, and in some types men are affected more often.
Night blindness can also have other causes, such as vitamin A deficiency; an eye examination tells them apart.
Symptoms and course
- Poor vision at night and in dim light
- Narrowing of peripheral (side) vision
Symptoms usually become noticeable after childhood. Vision loss progresses slowly, and severity varies from person to person.
Diagnosis, treatment and support
The diagnosis is made by examining the back of the eye and supported by tests such as visual fields, OCT and ERG.
An approved gene therapy exists for the type caused by the RPE65 gene, so genetic testing is important. For other types, low-vision aids, regular follow-up and genetic counselling provide support; research into new treatments is ongoing.
Frequently asked questions
What are the first symptoms?
It usually begins with poor night vision and narrowing of side vision.
Is there a treatment?
An approved gene therapy exists for the RPE65-related type; for other types, support and follow-up come first.
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This page is for general information only and does not replace a medical consultation. Anatomy and treatment plans differ from patient to patient.